Turn it off and on again: characteristics and control of torpor [version 2; peer review: 2 approved, 1 approved with reservations, 1 not approved]

Torpor is a hypothermic, hypoactive, hypometabolic state entered into by a wide range of animals in response to environmental challenge.This review summarises the current understanding of torpor.We start by describing the characteristics of the wide-ranging physiological adaptations associated with torpor.Next follows a discussion of She shed sign

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Differential effects of desvenlafaxine on hot flashes in women with breast cancer taking tamoxifen: a randomized controlled trial

Headwear Abstract Hot flashes (HF) are a common adverse event of prolonged tamoxifen use in women with estrogen receptor-positive breast cancer, impacting psychiatric health and quality of life.While desvenlafaxine does not interact with tamoxifen, its efficacy and safety in breast cancer patients remain unstudied.This phase 3, four-week, multi-cen

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Microcirculation disorders and structural and functional left ventricular abnormalities in patients with type 1 diabetes complicated by ketoacidosis

Aim.To assess the patterns of microcirculation disorders and its effect on the left ventricular (LV) structure and function in patients with type 1 diabetes (T1D) complicated by diabetic ketoacidosis Disposable Cutlery (DKA).Material and methods.The study included 128 patients with T1D complicated by DKA.Echocardiography was performed according to

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